SANTYL◊ Collagenase Ointment
250 units/gram
SANTYL Collagenase
Ointment is available in
the Canadian market.
To address the critical shortage, Health Canada has approved the temporary importation and sale of US-labelled SANTYL Ointment (250 units/g, Topical).
Key Details
• Order with this code 50484-010-30 to avoid backorder issues.
• The US product has the same formulation as the Canadian version.
Indication
SANTYL (collagenase) is a sterile ointment indicated for the debridement of dermal ulcers or severely burned areas
What is the mode of action
Collagenase digests collagen in the physiologic pH and temperature range. Since collagen accounts for 75% of the dry weight of skin tissue, collagenase is useful in the removal of detritus from the craters of dermal ulcers or skin burns. Rapid debridement contributes toward the formation of granulation tissue and subsequent epithelization of these lesions.
How to apply
For further guidance, please refer to the Canadian Product Monograph on the Drug Product Database.
Discover the benefits of SANTYL. Contact your sales representative!
Case Studies
SANTYL – Coleman BLE Case Study
Important Safety Information
Indications: SANTYL Ointment is a prescription only medication indicated for debriding dermal ulcers and severely burned areas.
Contraindications: SANTYL is contraindicated in patients who have shown local or systemic hypersensitivity to collagenase.
Warnings and Precautions: The optimal pH range of collagenase is 6 to 8. Higher or lower pH conditions will decrease the enzyme’s activity and appropriate precautions should be taken. The enzymatic activity is also adversely affected by certain detergents, and heavy metal ions such as mercury and silver which are used in some antiseptics. As such, the wound should be properly cleansed prior to application of SANTYL. Debilitated patients should be closely monitored for systemic bacterial infections because of the theoretical possibility that debriding enzymes may increase the risk of bacteremia. A slight transient erythema has been noted occasionally in the surrounding tissue, particularly when SANTYL was not confined to the wound.
Adverse Reactions: No allergic sensitivity or toxic reactions have been noted in clinical use when used as directed. The risk information provided herein is not comprehensive.
For complete prescribing information, please refer to the accompanying product information leaflet or visit the Drug Product Database. You are encouraged to report negative side effects of prescription drugs to Health Canada. Visit MedEffect Canada or call 1-866-234-2345.
◊Trademark of Smith+Nephew
